NRF2-p97-NRF2

Aryatara Shakya1, Pengfei Liu2, Jack Godek1

  • 1Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, AZ, 85721, USA.

Redox biology
|August 13, 2023
PubMed
概括

蛋白质p97负面调节NRF2,但NRF2也针对p97,创建一个反循环. 癌症的这种双重上调表明抑制NRF2和p97可能是治疗策略.

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