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阴茎切除术大小对初级开放角度眼光瘤治疗安全性和有效性的影响:一项多中心研究

Yu Zhang¹, Ping Yu², Yingzhe Zhang¹

¹From the State Key Laboratory of Ophthalmology (Yu Zhang, Yingzhe Zhang, F.L., Y.S., X.G., W.C., Xiulan Zhang), Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, Guangdong, China.

American journal of ophthalmology

|August 13, 2023

概括

120度,240度和360度的角膜切割 (GT),有或没有眼内透镜植入 (PEI) 的光乳化,对初级开角玻璃眼瘤 (POAG) 显示出类似的疗效. 这种360度切除术增加了高血风险.

科学领域:

眼科医生眼科眼科
玻璃眼的手术玻璃眼的手术
手术创新在外科创新.

背景情况:

主要开角青光眼 (POAG) 是全球不可逆转失明的主要原因.
目前的治疗方法旨在降低眼内压力 (IOP),但通常需要终身药物治疗或侵入性手术.
阴茎切除术 (GT) 是一种改善水性幽默外流的外科手术.

研究的目的:

为了比较120度,240度和360度骨切除术 (GT) 的疗效和安全性,在患有POAG的患者中,有或没有与眼内透镜植入 (PEI) 的法化.
评估不同程度的阴茎切除术和联合手术对IOP和药物使用的影响.
评估与每种手术方法相关的并发症率,特别是低血.

主要方法:

一个多中心的,回顾性,比较的,非随机的干预研究.
包括231名被诊断患有POAG.的患者的308只眼睛.
患者被分为六组:独立的120度,240度或360度GT,以及与PEI结合的GT.

主要成果:

在独立GT和联合PEI + GT组之间没有观察到IOP减少或药物减少的显著差异.
在所有组中,完全和合格成功率的累积生存概率在所有组中都是相似的.
与120度和240度组相比,360度GT组表现出较高的低血发病率,无论PEI如何.

结论:

带有或没有PEI的120度,240度和360度阴茎切割,通过减少IOP和药物负担,在管理POAG方面表现出相似的有效性.
360度阴茎切割与高血风险增加有关.
带有或没有PEI的120度阴道切除术是治疗POAG的充分选择,特别是当同时出现白内障时.

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