在接受心脏再同步治疗而没有除器的扩张性心肌病患者中,心律失常和死亡结果
Mohammed Samy1, Rehab M Hamdy2
1Cardiology Department, Faculty of Medicine (For Boys), Al-Azhar University, Cairo, 11765, Egypt.
Indian pacing and electrophysiology journal
|August 13, 2023
概括
没有除器 (CRT-P) 的心脏再同步治疗改善了对治疗有反应的扩张性心肌病患者的治疗结果. 这种方法可以降低成本和并发症,提高生存率和减少心室失常.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 心脏衰竭管理的管理
背景情况:
- 用除器 (CRT-D) 进行心脏再同步治疗的常规植入正在考虑扩张性心肌病 (DCM) 的患者.
- 对DCM患者的CRT中除器能力的必要性进行评估至关重要.
研究的目的:
- 调查在DCM患者中CRT植入后心律失常和死亡的结果.
- 评估这个特定的患者群体对除器能力的需求.
主要方法:
- 一项研究包括67名DCM患者,减少射出分数 (EF ≤35%),延长QRS持续时间 (>130毫秒),NYHAII-IV类,或具有节奏指示的患者.
- 患者接受了CRT与步调 (CRT-P),并根据36个月的临床和心声学改善评估了反应.
- 结果包括心室节律失常,全因死亡率和整体发病率.
主要成果:
- 与非响应者相比,CRT响应者在NYHA类,左心室喷射率 (LVEF) 和左心室末缩体积 (LVESV) 中显著改善.
- 受访者经历了明显较低的心室失常率,死亡率和全因发病率.
- 在响应者中观察到生存优势,与36个月的临床和心声回声CRT响应相关.
结论:
- 没有除备份的CRT-P植入对于DCM患者,特别是响应者来说是一个有前途的选择.
- 这种方法可能会节省成本,减少并发症,并改善结果,包括减少心室心律失常和提高生存率.
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