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在ibuprofen代谢上对CYP2C19和CYP3A4基因多态的功能评估

Ling-Jing Yuan1, Xiang-Yu Li2, Jin-Huan Ni3

  • 1Department of Pharmacy, Shaoxing Second Hospital, Shaoxing, Zhejiang, China.

Toxicology and applied pharmacology
|August 13, 2023
PubMed
概括

在CYP2C19和CYP3A4的遗传变异显著改变ibuprofen代谢. 这项研究描述了中国人群中的这些遗传差异,突出了由于药物清除的改变而导致药物不良反应的潜在风险.

关键词:
在CYP2C19中.在 CYP3A4 中.基因多态化是基因的多态化.伊布罗芬是什么意思?伊布罗芬是什么意思?

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