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系统性红斑狼中肠道参与的负担:一个比较的超声波研究

Ahmed Emerah¹, Shaimaa Mostafa¹, Lobna Kotb¹

¹Rheumatology and Rehabilitation Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Clinical rheumatology

|August 13, 2023

概括

肌肉骨超声波显示系统性红斑狼 (SLE) 患者的频繁肠炎,通常是亚临床的. 四头肌插入最受影响,肠炎的严重程度与SLE疾病活性相关.

科学领域:

类风湿病学类风湿病学
医疗成像医学成像
系统性自身免疫性疾病

背景情况:

肌肉骨 (MSK) 症状在全身性红斑狼 (SLE) 中很常见.
超声波是一种敏感的工具,用于诊断关节,肌和肠道部位的炎症和结构损伤.
识别肠道异常对于理解SLE表现至关重要.

研究的目的:

通过肌肉骨超声学 (MSUS) 确定SLE患者中肠道异常的流行和分布.
评估超声波脑内细胞变化与SLE疾病活性之间的关系.

主要方法:

一项涉及168名受试者的研究:56名SLE患者,56名牛皮关节炎 (PSA) 患者和56名健康对照.
在所有参与者身上进行了高分辨率的MSUS,以评估肠道部位.
马德里超声波脑膜炎指数 (MASEI) 用于比较脑膜炎的发生频率和分布.

主要成果:

在SLE患者中,亚临床肠炎的流行率高 (美国为71%;临床为39.3%).
脊椎肌的远端插入是最经常受到影响的部位 (41%的SLE患者).
与对照组 (19.6%) 相比,PSA患者 (100%) 和SLE患者 (71.4%) 的肠炎发生率明显高.
在MASEI得分和SLE疾病活性 (SLEDAI),24小时总蛋白质之间发现了显著的相关性,以及与血清白蛋白的反相关性.

结论:

脑膜炎在SLE患者中很常见,无论是在临床上还是超声波上.
四头肌插入处是最常受到冲击的肠道部位.
肠炎的存在和MASEI得分可以表明SLE疾病的严重程度.

关键词:

脑膜炎是一种脑膜炎.牛皮病是什么意思牛皮病系统性红血性狼 (Systemic lupus erythematosusus) 是一种全身性狼.美国美国美国

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