尾神经内分泌新生体:一个全面的审查
Renjith Padmanabhan Nair Sobha1, Corey T Jensen1, Rebecca Waters2
1From the Department of Radiology, University of Texas MD Anderson Cancer Center.
Journal of computer assisted tomography
|August 14, 2023
概括
尾神经内分泌瘤 (NENs) 是常见的,多功能瘤经常偶然发现. 本综述涵盖了它们的诊断,分期和治疗,包括先进疗法和生物标志物研究.
科学领域:
- 胃肠道学和瘤学
- 病理学和放射学 病理学和放射学
背景情况:
- 尾神经内分泌瘤 (NENs) 是尾最常见的恶性瘤.
- 这些瘤表现出不同的形态,分泌功能和基因组形状,通常呈现无症状或含有模糊的腹痛.
研究的目的:
- 提供附录NENs的全面概述.
- 详细描述成像,组织病理学分类,分期和早期和高级阶段的管理指南.
主要方法:
- 关于附录NENs的当前文献的综述.
- 专注于成像特征,世卫组织分类,AJCC/UICC和ENETS分期系统.
- 讨论治疗方案,包括向治疗和随访.
主要成果:
- 尾NEN通常在尾切除术后偶然检测到,尽管有些存在激素过量 (癌症综合征).
- 高度瘤可以具有攻击性,在呈现时转移.
- 该审查综合了报告,解释和管理的指导方针.
结论:
- 附录性NEN的有效管理需要采用综合成像,病理学和分期的多学科方法.
- 先进的治疗方法,如放射治疗,化疗和体静止素类似物,对于晚期疾病至关重要.
- 对特定位置生物标志物和瘤生物学进行进一步的研究是有必要的.
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