饮食和血清胆固醇与美国人认知功能之间的关联 来自NHANES 2011-2014年级的老年人
Sheng Huan1,2, Mengling Liu2, Ziqiu Liu2,3
1Department of Anesthesiology and Perioperative Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, P.R. China.
Journal of Alzheimer's disease : JAD
|August 14, 2023
概括
血清胆固醇可以支持老年人的认知功能,但饮食胆固醇.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 认知神经科学 认知神经科学
背景情况:
- 饮食/血清胆固醇与老年人认知功能之间的关系尚不清楚.
- 现有研究尚未确定这些关联.
研究的目的:
- 检查饮食和血清胆固醇水平与老年人的认知表现之间的联系.
- 探索这些协会中潜在的种族差异.
主要方法:
- 国家健康和营养检查调查 (NHANES) 数据 (2011-2014) 的横截面分析.
- 从24小时回忆中估计的饮食胆固醇;通过统计测试评估认知功能.
- 根据人口统计学调整的分析,对非西班牙裔白人 (NHW) 和非西班牙裔黑人 (NHB) 个人进行子组检查.
主要成果:
- 饮食中的胆固醇与整体认知功能没有关联,除了NHB个体的积极联系.
- 血清总胆固醇与一般样本和NHW参与者的认知表现正相关.
- 血清胆固醇和认知之间的关联在NHB个体中不太常见.
结论:
- 血清胆固醇在正常范围内升高可能有助于预防或减轻老年人认知能力下降.
- 种族差异很大,在评估胆固醇对认知表现的影响时必须考虑.
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