在帕金森病中结步态:双重任务行走的含义
Andrew S Monaghan1, Anjanibhargavi Ragothaman2, Graham R Harker2
1College of Health Solutions, Arizona State University, Phoenix, AZ, USA.
Journal of Parkinson's disease
|August 14, 2023
概括
患有帕金森病的人,经历结的步态,具有更大的双重任务成本,特别是在步态参数. 认知和性别也影响了帕金森病的双重任务成本.
科学领域:
- 神经科学是一个神经科学.
- 生物医学工程 生物医学工程
- 运动科学 运动科学
背景情况:
- 双重任务 (DT) 涉及同时执行多个任务,往往导致性能降低 (双重任务成本,DTC).
- 患有帕金森病 (PwPD) 的人经常与DT作斗争,那些经历了步态结 (FOG) 的人可能有更高的DTC.
研究的目的:
- 在PwPD中调查FOG状态和DTC在步行过程中的关系.
- 为了确定在PwPD中受DT影响的步态参数,具有不同的FOG严重程度.
主要方法:
- 从106 PwPD (非药物治疗) 使用惯性传感器收集的步态参数.
- 分类参与者为确定的冷机 (dFOG),可能的冷机 (pFOG) 和非冷机 (nFOG).
- 在单任务 (ST) 和DT行走过程中比较DTC.
主要成果:
- 与nFOG相比,患有dFOG的PwPD在足部冲击角度,步伐长度,脚偏离角度,步态变化和手臂运动范围方面表现出明显较差的DTC.
- 认知功能预测了脚步长度,步态周期持续时间,步态速度和步态持续时间的增加DTC.
- 男性参与者在步行速度,步伐长度和手臂运动范围方面显示出更大的DTC;增加的DTC变化与疾病严重程度相关.
结论:
- 在PwPD中结步态可能需要更大的皮质参与,以便在双重任务期间控制步态.
- 认知状态是评估PwPD中DT表现的关键因素.
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