系统性审查和对人口体育不活动归因于痴呆症的比例的元分析
Natan Feter1, Jayne S Leite2, Luísa Silveira da Silva3
1Post Graduate Program in Epidemiology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
概括
身体不活动有助于痴呆病例,估计范围广泛. 谨慎地说,每15例痴呆病例中就有1例可能与身体不活动有关.
科学领域:
- 公共卫生 公共卫生
- 神经学 神经学
- 流行病学 流行病学
背景情况:
- 身体不活动是一个日益严重的全球健康问题.
- 身体不活动对痴呆症发病率的确切贡献尚未得到充分证实.
- 定义和方法的异质性使准确的估计变得复杂.
研究的目的:
- 系统地审查和综合有关痴呆症身体不活动人口归因分数 (PAF) 的证据.
- 提供与身体不活动相关的痴呆病例的综合估计.
主要方法:
- 对基于人口的研究进行系统审查,估计痴呆症的PAF.
- 包括22项研究,对身体不活动的定义不同.
- 根据共享风险因素调整的加权PAF.
主要成果:
- 身体不活动对痴呆的整体影响在6.6% (加权) 到16.6% (未加权) 之间.
- 使用世卫组织身体不活动标准的研究报告了更高的未加权影响.
- 根据身体不活动的定义和统计方法,估计数量有所不同.
结论:
- 身体不活动是痴呆症的重要,可修改的风险因素.
- 一项保守的估计表明,每15例痴呆症病例中,就有1例是由于身体不活动造成的.
- 为了准确的未来估计,需要标准化的定义和方法.
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