女性发型脱发亚型的人口统计和临床特征的差异
Nawara Sakpuwadol1, Kasama Tejapira1, Chaninan Kositkuljorn1
1Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Clinical, cosmetic and investigational dermatology
|August 14, 2023
概括
女性发型脱发 (FPHL) 亚型表现出不同的特征. 汉密尔顿-诺伍德亚型与早期发病和PCOS有关,而路德维格和奥尔森亚型与2型糖尿病有关.
科学领域:
- 皮肤病学 皮肤病学
- 内分泌学 在内分泌学.
- 流行病学 流行病学
背景情况:
- 女性发型脱发 (FPHL) 是女性最常见的脱发,其中包括路德维格,奥尔森和汉密尔顿-诺伍德等亚型.
- 仅有有限的数据可以比较FPHL亚型中的人口统计,临床特征和并发症.
研究的目的:
- 为了比较FPHL亚型的流行病学,临床表现和并发症状况.
- 为了确定与每个FPHL亚型相关的因素.
主要方法:
- 在2000年至2021年期间诊断出519名FPHL患者的回顾性研究.
- 分类为路德维格,奥尔森和汉密尔顿-诺伍德亚型.
- 多变量多项逻辑回归分析以确定相关因素.
主要成果:
- 路德维格 (51.1%) 是最常见的亚型,其次是奥尔森 (32.9%) 和汉密尔顿-诺伍德 (16%).
- 汉密尔顿-诺伍德亚型显示出更高的早期发病频率,月经不规则,PCOS和斑疹,但超重和2型糖尿病的频率较低.
- 多变量分析证实汉密尔顿-诺伍德作为早期发病和PCOS的预测因子,反之为2型糖尿病.
结论:
- 路德维格模式是泰国患者中最常见的FPHL亚型.
- 汉密尔顿-诺伍德亚型与早期疾病发病和PCOS有关.
- 路德维格和奥尔森亚型与2型糖尿病有关.
相关概念视频
Accessory Structures of the Skin: Hair Growth and Types
1.5K
Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
1.5K
Panic Disorder
144
Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
144
Multipotency and Niche of Bulge Stem Cell
3.7K
A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
3.7K
Accessory Structures of the Skin: Hair and Hair Follicles
2.4K
Hair and hair follicles are integral components of the integumentary system. Hair is a filamentous structure composed mainly of a protein called keratin. It is found on the surface of the skin throughout the body, except for areas such as the palms of the hands and soles of the feet.
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
Hair is a keratinous filament growing out of the epidermis. It is primarily made of dead, keratinized cells. Hair strands originate at the epidermal penetration called the hair follicle. The hair shaft is the part...
2.4K
Disorders of the Female Reproductive System
408
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
408
Folliculogenesis
867
Folliculogenesis is the development of ovarian follicles, the specialized structures within the ovarian cortex where oogenesis, or egg development, occurs. This process is essential for female reproductive health and begins during fetal development when primordial follicles are formed. Each primordial follicle comprises a primary oocyte in the center, surrounded by a single layer of squamous pre-granulosa cells. These follicles remain dormant in late prophase I of meiosis until triggered by...
867


