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Updated: Jul 19, 2025

In Vitro Stimulation and Visualization of Extracellular Trap Release in Differentiated Human Monocyte-derived Macrophages
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内皮外体作为一个功能调解者来激活巨细胞

Wenwen Lin1,2,3,4,5, Feng Huang1,2,3,4,5, Yin Yuan1,2,3,4,5

  • 1Department of Geriatric Medicine, Fujian Provincial Hospital, Fuzhou, China.

Frontiers in immunology
|August 14, 2023
PubMed
概括

炎症的内皮外体 (exo-T) 通过激活MAPK/NF-κB信号通路来促进巨细胞 (Mφ) M1极化,脂质沉积和亡. 这些发现突出了exo-T作为动脉样硬化病变发生的关键媒介.

关键词:
动脉样硬化 动脉样硬化细胞内皮细胞的内皮细胞.外基因组是外基因组的组成部分.巨细胞是一个巨细胞.瘤死亡因子-α

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