冠状动脉心脏病严重程度与随后的慢性鼻炎严重程度之间的相关性:一个回顾性队列研究
Ke-Hsin Ting1,2,3, Yen-Ting Lu4,5,6, Chung-Han Hsin4,5
1Division of Cardiology, Department of Internal Medicine, Changhua Christian Hospital, Yunlin Branch, Yunlin, Taiwan.
International journal of medical sciences
|August 14, 2023
概括
被冠状动脉旁路移植 (CABG) 治疗的严重冠状动脉病 (CHD) 患者患慢性鼻炎 (CRS) 的风险更高. 这种关联在男性中尤为明显,突出显示了CHD严重程度和CRS发病率之间的联系.
科学领域:
- 心脏病学 心脏病学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 流行病学 流行病学
背景情况:
- 冠心病 (CHD) 是一种与各种并发症相关的严重心血管疾病.
- 慢性鼻炎 (CRS) 是上呼吸道的炎症状况,具有复杂的病因.
- 了解诸如心脏病和慢性复发性复发性等全身性疾病之间的关系对于全面的患者护理至关重要.
研究的目的:
- 调查冠心病 (CHD) 的严重程度与慢性鼻炎 (CRS) 的随后发展之间的关联.
- 为了比较CRS和严重CRS发生率在轻度心血管疾病 (皮肤冠状动脉干预,PCI) 与严重心血管疾病 (冠状动脉旁路移植,CABG) 的患者中.
主要方法:
- 基于人口的回顾性队列研究,利用台湾国家健康保险研究数据库.
- 根据治疗方法对心脏病严重程度的分类:轻度 (PCI) 和严重 (CABG).
- 考克斯比例危险回归分析,以确定CRS发展的调整危险比率 (aHR).
主要成果:
- 总共分析了CHD-PCI组的31,784名患者和CHD-CABG组的15,892名患者.
- 与CHD-PCI组相比,CHD-CABG组的CRS发病率显著更高 (aHR: 1.196,95%CI: 1.064-1.280).
- 严重CRS的发病率在各组之间没有显著差异,但亚组分析表明,男性中CHD严重程度和CRS之间存在更强的关联.
结论:
- 用CABG治疗的严重心脏病与随后的CRS发病率的增加有关.
- 严重的心脏病和CRS发展之间的联系在男性患者中更为明显.
- 进一步的研究可能会探索连接心血管健康和鼻炎症的潜在机制.
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