怀孕和儿童发育期间母亲的食纤维摄入量:日本环境和儿童研究
Kunio Miyake1, Sayaka Horiuchi2, Ryoji Shinohara2
1Department of Health Sciences, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Chuo, Japan.
Frontiers in nutrition
|August 14, 2023
概括
怀孕期间母亲的低纤维饮食与儿童神经发育迟缓的风险增加有关. 这项流行病学研究强调了充足的食纤维对健康后代大脑发育的重要性.
科学领域:
- 流行病学 流行病学
- 神经科学是一个神经科学.
- 营养科学 营养科学
背景情况:
- 动物研究表明,母亲的低纤维饮食会损害后代的大脑发育.
- 在人类中缺乏这种联系的流行病学验证.
- 这项研究通过检查母亲的纤维摄入量和神经发育迟缓来弥补这一差距.
研究的目的:
- 调查孕期母亲饮食纤维摄入量与后代神经发育迟缓之间的关联.
- 利用来自大规模前性出生队列研究的数据.
主要方法:
- 来自日本环境和儿童研究的76,207对母婴对的分析.
- 在怀孕中期通过食物频率问卷评估母亲的食纤维摄入量.
- 在3岁时使用年龄和阶段问卷 (ASQ-3) 评估发育迟缓.
主要成果:
- 总食纤维摄入量的最低五分位数与较高的延迟沟通,精细运动技能,解决问题和个人社交技能的几率有关.
- 对于这些延迟,调整后的赔率比率 (aOR) 从1.30到1.51不等.
- 即使排除了叶酸摄入不足的影响,也观察到类似的趋势.
结论:
- 怀孕期间母亲的食纤维缺乏可能会增加后代神经发育迟缓的风险.
- 这些发现强调了足够的纤维摄入对于胎儿神经发育的重要性.
- 进一步的研究可能会探索与母亲饮食和儿童神经发育有关的特定机制.
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