在接受阿片类药物维持治疗的患者中,抑郁症和自杀念头,考虑到认知灵活性
Mojtaba Rajabpour1, Majid Mirmohammadkhani2,3, Fatemeh Paknazar2,3
1Physiology Research Center, Semnan University of Medical Sciences, Semnan, Iran.
Iranian journal of psychiatry
|August 14, 2023
概括
认知灵活性与接受阿片类维持治疗 (OMT) 的患者的较低抑郁症有关. 虽然与自杀风险没有直接关联,但提高认知灵活性可能有助于减少这一群体的抑郁症.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 成 药物 药物 药物 药物
背景情况:
- 认知灵活性至关重要,在精神疾病中经常受到损害.
- 患有物质使用障碍的人经常经历并发的精神疾病.
- 阿片类药物维持治疗 (OMT) 是阿片类药物使用障碍的常见干预措施.
研究的目的:
- 研究接受OMT的患者的认知灵活性,抑郁和自杀念头之间的关系.
- 探索认知灵活性在OMT和精神病结果之间的关联中扮演的调解角色.
主要方法:
- 一项涉及126名OMT (甲,布普伦诺芬,青) 禁欲至少一年的患者的横截面研究.
- 数据采用贝克抑郁症目录II (BDI-II),贝克自杀念头量表 (BSSI) 和认知灵活性目录 (CFI) 来收集.
- 统计分析使用后勤回归模型来评估相关性和关联.
主要成果:
- 在抑郁症,自杀念头和认知灵活性之间发现了显著的相关性.
- 增加的认知灵活性与抑郁症的可能性降低有关 (OR = 0.87).
- 与美沙相比,布普伦诺芬和片剂治疗与抑郁症的增加有关;认知灵活性不能独立预测自杀风险.
结论:
- 接受OMT治疗的患者表现出不同程度的抑郁和自杀念头.
- 在OMT患者中,认知灵活性与抑郁和自杀念头相关.
- 认知训练干预可能有助于减少这种患者群体的抑郁症.
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