相关实验视频
Updated: Jul 19, 2025

10:43
Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
Published on: December 23, 2022
3.4K
食道颗粒细胞瘤:一种不常见的失症原因
Richard A Revia1, Raj Shah2,3, Amar Mandalia4
1Pathology, University of Central Florida College of Medicine, Orlando, USA.
Cureus
|August 14, 2023
概括
颗粒细胞瘤 (GCTs) 是一种罕见的食道瘤,可以引起食不适. 通过EGD和EUS进行早期诊断,然后进行内镜切除,有效地治疗这种难以吞的不常见原因.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 颗粒细胞瘤 (GCTs) 是一种罕见的新生体,具有多种位置.
- 食道GCTs可能会导致食欲障碍,这种症状通常归因于更常见的疾病.
- 在食障碍的差异诊断中,GCT经常被忽视.
研究的目的:
- 提高人们对食道GCTs作为失消症的原因的认识.
- 强调这种罕见瘤的诊断和管理策略.
- 介绍一个成功内镜治疗食道GCT的案例.
主要方法:
- 消化管胃管腺镜 (EGD) 用于病变的可视化.
- 内镜超声波 (EUS) 用于亚皮质病变的表征.
- 组织病理学和免疫组织化学分析的活检,以确定诊断.
- 内镜粘膜切除 (EMR) 用于瘤的去除.
主要成果:
- 通过EGD和EUS,通过EGD和EUS确定了一个亚皮质食道质量.
- 组织病理学证实了质量作为一个GCT.
- 在EMR之后,患者的消化不良完全消失.
- 随访显示,GCT没有复发.
结论:
- 食道GCT是一种不常见但可治疗的失消症原因.
- 在评估亚皮质食道病变时,EGD和EUS是至关重要的.
- 组织病理学分析对于确定GCT诊断至关重要.
- 在食道GCT方面,EMR提供了一种成功的治疗选择.
相关概念视频
Esophageal Strictures-I: Introduction
140
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
140
Barrett Esophagus-II: Clinical Manifestations and Management
195
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
195
Barrett Esophagus-I: Introduction
123
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
123
Esophageal Strictures-II: Clinical Features and Management
103
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
103
Gastroesophageal Reflux Disease I: Meaning and Pathophysiology
350
Gastroesophageal Reflux Disease (GERD) involves the recurrent backflow of the stomach or duodenal contents into the esophagus, leading to troublesome symptoms and potential esophageal mucosal damage. Although GERD is often referred to as a disease, it is more accurately described as a syndrome, as it encompasses a range of symptoms and complications rather than a singular pathological entity, impacting a large number of individuals as the most prevalent upper gastrointestinal problem. Roughly...
350
Esophageal Perforation-I: Introduction
123
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
123

