计算的血体积状况与急性缺血性中风的不良结果有关,这些中风与血管内治疗治疗有关
Dixia Zhang1, Qiuru Li1, Jun Liu1
1Department of Neurology, The Sixth People's Hospital of Chengdu, Chengdu, China.
Frontiers in neurology
|August 14, 2023
概括
高血量状态 (PVS) 与急性缺血性中风 (AIS) 患者接受内血管治疗 (EVT) 的不良结果有关. 这一发现强调了PVS作为接受EVT的AIS患者的潜在预后标志物.
科学领域:
- 神经学 神经学
- 心血管医学 心血管医学
- 医疗成像医学成像
背景情况:
- 在接受内血管治疗 (EVT) 的急性缺血性中风 (AIS) 患者中,血体积状态 (PVS) 的预后值尚未得到充分确立.
- PVS是一种计算的指标,反映了血液循环系统中的血体积.
研究的目的:
- 调查用EVT治疗的AIS患者计算的PVS和90天功能结果之间的关联.
- 确定PVS是否可以作为治疗成功的预测因素.
主要方法:
- 一个前性注册表被用于注册接受EVT的患者,以获得前部循环AIS.
- 功能性结局被定义为在EVT后90天的Rankin尺度修改分数≥3的功能性结局.
- 采用多变量逻辑回归和受限立方线模型来分析PVS和糟糕结果之间的关系.
主要成果:
- 在187名患者中,43.3%的患者在90天后出现了不良结果.
- 即使调整了混因素 (OR,3.157;95% CI,1.942-5.534;P < 0.001) 后,PVS也与糟糕的结果有显著的关联.
- 在PVS和不良结果的风险之间观察到正相关性 (P为非线性=0.021).
结论:
- 升高的PVS与在EVT后患有AIS的患者的不良功能结果有关.
- 在这种患者群体中,PVS可能是一个有价值的预后指标.
- 需要进一步的前性研究来确认PVS在EVT的AIS管理中的临床实用性.
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