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饮食中的能够影响维生素C与估计的膜过率之间的关系:一个横截面研究
Zheng-Yang Lin1, Yong-Yi Liang2, Ru Wang3
1Department of Clinical Medicine The Second Clinical School of Guangzhou Medical University Guangzhou China.
Food science & nutrition
|August 14, 2023
概括
饮食中的维生素C对功能产生积极影响 (eGFR). 这种效应在低摄入量的人群中得到了放大,突出了这些营养素在估计的膜过率之间显著的相互作用.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 估计的膜过率 (eGFR) 是功能的一个关键指标.
- 以前的研究表明,食维生素C和eGFR之间存在联系,但其与其他营养素的确切影响和相互作用尚未完全理解.
- 饮食中的和维生素C与eGFR之间的相互作用需要进一步研究.
研究的目的:
- 研究饮食摄入量,维生素C和eGFR之间的关系.
- 探索食对维生素C摄入量和eGFR之间的关联的潜在相互作用效应.
主要方法:
- 分析了NHANES数据库 (2005年至2018年) 中17633名参与者 (年龄≥20岁) 的数据.
- 用多种线性回归模型来评估食维生素C与eGFR之间的关联.
- 饮食摄入量被分为低 (≤254毫克/天) 和正常 (>254毫克/天) 组,并进行相互作用测试.
主要成果:
- 在饮食中的维生素C摄入量和eGFR之间发现了显著的积极关联.
- 维生素C对eGFR的积极影响在摄入低的人群中比摄入正常的人群更为明显.
- 饮食中的摄入量显著改变了饮食中的维生素C和eGFR之间的关联 (相互作用p=0.020).
结论:
- 饮食中的和维生素C之间的相互作用显著影响eGFR.
- 这些发现表明,优化和维生素C摄入量可能对管理功能至关重要.
- 这对临床实践有影响,包括疾病治疗和与异常EGFR相关的疾病的药物选择.
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