前庭动激活模式预测了导管切除后没有心律失常的情况:ExTRa映射TM的实用性
Daisetsu Aoyama1, Shinsuke Miyazaki2, Kanae Hasegawa1
1Department of Cardiovascular Medicine, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.
Frontiers in cardiovascular medicine
|August 14, 2023
概括
心房动 (AF) 的激活模式,特别是左心室高的非被动激活比率,预测了切除后的复发. 绘制这些模式可以指导AF患者的治疗成功.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 前庭动 (AF) 的机制复杂且个体特异.
- 了解AF驱动因素对于有效治疗至关重要.
- 目前的切除策略旨在消除心律失常源.
研究的目的:
- 调查AF激活模式与切除后临床结果之间的关联.
- 为了确定AF切除后心律失常复发的预测因素.
- 评估实时阶段映射在指导废弃策略中的实用性.
主要方法:
- 55名AF患者进行双心房内心驱动器映射的回顾性研究.
- 使用实时相位映射系统 (ExTRa映射) 来评估非被动激活比率 (%NP).
- 进行了标准AF切除,随后进行了27个月的中位数随访.
主要成果:
- 一年后,69.1%的患者没有复发性心律失常.
- 更高的LA最大%NP (LAmax%NP) 和LA前壁%NP (LAAW%NP) 与复发性AF相关.
- LAmax%NP (>64.5%) 和LAAW%NP (>60.0%) 独立预测了心律不整的复发 (HRs >1.06).
结论:
- 基线AF激活模式映射可以预测切除后心律失常的复发.
- LAmax%NP和LAAW%NP是AF复发的重要预测因素.
- 绘制地图可能有助于个性化AF切除策略,以改善结果.
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