帕金森病中叙事话语的产生:解脱认知语言和运动语言变化的作用
Sara D'Ascanio1, Fabrizio Piras1, Nerisa Banaj1
1Neuropsychiatry Laboratory, Department of Clinical Neuroscience and Neurorehabilitation, IRCCS Santa Lucia Foundation, Rome, Italy.
Heliyon
|August 14, 2023
概括
帕金森病 (PD) 的叙述性话语受损,生产力和信息性降低与命名能力有关,而不是运动语言问题. 这些发现强调了评估PD管理中的话语的重要性.
科学领域:
- 神经科学是一个神经科学.
- 语言学的语言学.
- 语音语言病理学 语音语言病理学
背景情况:
- 帕金森病 (PD) 影响认知和沟通功能,但神经心理和沟通能力之间的相互作用,特别是在叙事话语中,仍然不清楚.
- 区分运动控制缺陷和PD沟通障碍中的语言/认知因素对于有效的干预至关重要.
研究的目的:
- 为了调查轻度阶段帕金森病 (PD) 中的叙事话语改变.
- 区分语言,执行和运动语言能力对PD叙事障碍的贡献.
- 探索叙事话语分析在早期发现PD认知衰退方面的潜力.
主要方法:
- 将29名轻度PD患者与29名健康比较者 (HC) 进行比较,使用从图片描述任务中获得的叙事话语的定量测量.
- 采用了句子层面 (生产力,词汇-语法处理) 和话语层面 (叙事组织,信息化) 过程的多层次分析.
- 使用多变量和单变量分析差异,控制关节率和教育成就,以及多重回归来探索认知贡献.
主要成果:
- 患有PD的患者在叙事生产力 (词汇形成,句子长度) 和信息性 (概念单位,细节) 显著下降.
- 这些叙事缺陷主要与语言能力受损有关,特别是行动和对象命名 (动词处理),而不是执行功能.
- 运动语言障碍 (发音率) 和教育程度并没有显著影响观察到的生产力和信息能力的下降.
结论:
- 在帕金森病中,参考叙事话语被明显改变,独立于运动语言障碍.
- 观察到的叙事障碍与潜在的命名和动词处理缺陷有关,与语言和运动控制的神经认知模型保持一致.
- 建议在PD中对话语能力进行定量和重复分析,以早期识别语言模式和认知恶化.
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