白化揭示了一个计数矩阵的等级
Boris Landa1, Thomas T C K Zhang2, Yuval Kluger1
1Program in Applied Mathematics, Yale University.
概括
我们介绍了双白化,这是一种用于估计计数数据矩阵的排名的新方法,对于主要组件分析 (PCA) 至关重要. 这种技术有效地处理Poisson和相关计数数据中的异构分级噪声,提高排名估计的准确性.
科学领域:
- 数据科学数据科学数据科学
- 统计学学习 统计学学习
- 矩阵分析是一门学科.
背景情况:
- 估计矩阵排名对于主要组件分析 (PCA) 和数据分析至关重要.
- 传统方法在计数数据矩阵 (例如,Poisson) 上因异构杂而扎.
- 随机矩阵理论提供了工具,但需要适应计数数据.
研究的目的:
- 开发一种可靠的方法来估计具有未知方差的波桑随机矩阵的等级.
- 为了应对对排位估计计计数数据中异构排列噪声的挑战.
- 为各种计数分布和缺失数据提供一种可概括的方法.
主要方法:
- 提出了一种双白化程序来缩放数据矩阵.
- 保证的噪声频谱符合马尔琴科-帕斯图尔 (MP) 关于等级选择的法律.
- 利用Sinkhorn-Knopp算法从观察中估计缩放因子.
主要成果:
- 在没有事先知识的情况下,Biwhitening有效地估计了Poisson参数矩阵的排名.
- 该方法扩展到具有二次平均变量关系的其他分布 (例如二项式,玛).
- 数字实验和现实世界数据集 (scRNA-seq,Hi-C,主题建模) 验证了该方法.
结论:
- Biwhitening提供了一种强大而通用的工具,用于在损坏的计数数据矩阵中进行排名估计.
- 该方法在具有挑战性的场景和各种应用中表现出卓越的性能.
- 这项工作在各种科学领域推进了基于计数的数据分析.
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