在选择性整形外科手术中减少阿片类药物的多模式止痛方案的比较:一项随机研究
Katherine L Long-Lijoi1, Hrijeeta Mukherjee2, Ximena A Pinell2
1From the Drexel University College of Medicine, Reading, Pa.
Plastic and reconstructive surgery. Global open
|August 14, 2023
概括
一种非类固醇抗炎药物 (NSAID) 疗法表明,与 gabapentin 相比,在美容手术后的疼痛管理中,患者满意度更高,并发症更少. 这两种方法都有效地减少了疼痛,有助于打击阿片类药物过度处方.
科学领域:
- 疼痛管理 疼痛管理
- 术后恢复 术后恢复
- 药理学 药理学是指药理学的学科.
背景情况:
- 多种模式的止痛疗法对于美容手术后的术后疼痛管理至关重要.
- 加巴丁和非类固醇抗炎药 (NSAIDs) 是止痛药的常见组成部分.
- 在最大限度地减少阿片类药物使用的同时优化疼痛控制是手术恢复的关键目标.
研究的目的:
- 为了比较基于加巴丁的多种模式止痛疗法的疗效和安全性,与在整形外科手术后基于NSAID的疗法相比.
- 为了评估两种止痛方案之间的患者满意度,遵从性和并发症率.
主要方法:
- 一项前性随机研究,涉及106名接受选择性门诊整形手术的患者.
- 患者被分配到 gabapentin 或 NSAID 多模式治疗方案中,收集了关于疼痛水平,药物使用,满意度和并发症的数据.
- 进行了统计分析,以比较两个组之间的结果.
主要成果:
- 这两种疗法都提供了同等的疼痛控制,除了麻醉后护理单元 (PACU).
- 无 NSAID 组显示了显著更高的遵守 (9.3%),患者满意度 (6.0%) 和更短的间隔到PACU入院 (25.2%).
- 此外,NSAID组的出血相关并发症发生率显著降低 (8.2%).
结论:
- gabapentin 和 NSAID 疗法都有效降低术后疼痛,并对抗阿片类药物过度处方.
- 该NSAID协议在患者满意度,成本效益和减少并发症方面提供了优势.
- 由于NSAIDs具有有利的安全性和合规性,因此支持在手术后加强恢复的使用.
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