旅行距离与HPV相关癌症的总生存率在高负担状态中的关系
Sameer Vali Gopalani1, Hanh Dung Dao1, Lance Ford1
1Department of Biostatistics and Epidemiology, Hudson College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104.
Journal of registry management
|August 14, 2023
概括
与人类乳头瘤病毒 (HPV) 相关的癌症患者前往更远的治疗中心的患者的生存结果更差. 这凸显了旅行负担对癌症患者存活率的影响,以及对可访问护理的需求.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 专业癌症护理的地理可用性会影响患者的治疗结果.
- 人类乳头瘤病毒 (HPV) 相关的癌症是一个重大的公共卫生问题.
- 了解旅行距离在癌症生存中的作用对于医疗保健规划至关重要.
研究的目的:
- 调查在被诊断患有HPV相关癌症的患者中,到达学术卫生系统的旅行距离和整体存活率之间的关联.
- 量化不同旅行距离对患者生存率的影响.
主要方法:
- 利用了2005-2019年医院癌症登记数据.
- 使用网络分析计算单向旅行距离,从患者地址到学术医疗中心.
- 采用多变量Cox比例危险回归来分析生存数据,将距离分类为短距离 (<25英里),中间距离 (25-74.9英里) 和长距离 (≥75英里).
主要成果:
- 与短距离旅行相比,中长距离旅行的HPV相关癌症患者面临更高的死亡风险 (HR分别为1.23和1.15).
- 最低的调整后的5年生存率是在中距离组 (60.4%) 中观察到的,其次是远距离 (62.6%) 和短距离 (66.2%) 组.
结论:
- 到学术医疗中心的旅行距离与HPV相关癌症患者的整体存活率有显著的关联.
- 这些发现强调了解决旅行负担的重要性,这是改善HPV相关癌症患者治疗结果的关键因素.
- 减轻与旅行有关的障碍的策略可能会提高这种患者群体的存活率.
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