患者报告的肺癌症状影响 (PRISM-LC)
Anika Varma1, Jennifer Weinstein1, Jamison Seabury1
1Center for Health + Technology, University of Rochester, CU, Rochester, NY, USA.
Translational lung cancer research
|August 14, 2023
概括
肺癌 (LC) 患者会出现显著的症状,如疲劳和睡眠问题. 残疾状况与症状患病率有很强的相关性,影响日常生活,需要以患者为中心的护理.
科学领域:
- 在瘤学瘤学.
- 患者报告的结果
- 症状科学 症状科学
背景情况:
- 肺癌 (LC) 呈现出各种症状,影响患者的生活质量.
- 了解症状的流行和负担对于有效的管理至关重要.
- 患者的意见对于识别关键症状和相关的人口因素至关重要.
研究的目的:
- 识别和优先考虑患有肺癌的个体所经历的症状.
- 确定各种症状主题的流行程度和影响.
- 探索肺癌患者的症状负担与人口统计学关联.
主要方法:
- 半结构化的定性访谈,以确定潜在的症状.
- 与139名肺癌患者进行的横截面研究,在14个主题中评价了162种症状.
- 根据人口统计学因素分析症状数据,包括年龄,性别,残疾,LC阶段,治疗和吸烟史.
主要成果:
- 最常见的症状:疲劳 (85.5%),睡眠障碍/白天嗜睡 (73.5%),以及情绪问题 (73.0%).
- 影响最大的症状:社会角色不满 (1.67),无法进行活动 (1.64),疲劳 (1.60).
- 残疾状况与症状患病率的关联最强;LC阶段,治疗和吸烟史也与此相关.
结论:
- 肺癌患者面临着一系列具有影响力的症状.
- 患者报告的结果对于开发有针对性的治疗干预措施至关重要.
- 解决症状负担,特别是与残疾相关的问题,是改善肺癌护理的关键.
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