在卡布基综合征小鼠中,CpG岛屿和与衰老相关的区域的神经特异性染色质破坏

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Leandros Boukas1,2,3, Teresa Romeo Luperchio2, Afrooz Razi2

  • 1Department of Pediatrics, Children's National Hospital.

bioRxiv : the preprint server for biology
|August 14, 2023
PubMed
概括

表观遗传调节者的变异会导致发育障碍,但染色质破坏在细胞类型之间有所不同. 神经元表现出独特的变化,这表明血液检测可能无法揭示神经发育机制.

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