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在急性髓性白血病的全基移植之前可测量的残留IDH1

Gege Gui1,2, Laura W Dillon1, Niveditha Ravindra1

  • 1Laboratory of Myeloid Malignancies, Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.

medRxiv : the preprint server for health sciences
|August 14, 2023
PubMed
概括

在急性髓性白血病 (AML) 的干细胞移植前检测血液中的IDH1突变并不能预测复发风险. 只有NPM1或FLT3-ITD突变表明AML患者的复发率更高.

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Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
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