在查静音肝病时使用振动控制的暂时弹性图谱
Ebada Said1, Muhammad Abdel-Gawad2, Eman Abdelsameea3
1Hepatology, Gastroenterology and Infectious Diseases Department, Benha Faculty of Medicine, Benha University, Banha.
European journal of gastroenterology & hepatology
|August 14, 2023
概括
大多数看似健康的成年人有沉默的肝脏疾病,如脂肪和纤维化. 振动控制的短暂弹性图形学和控制的衰减参数 (CAP) 显示出对一般人群中这些肝病的非侵入性查有前途.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 诊断成像 诊断成像 诊断成像
- 非侵入性肝脏评估评估
背景情况:
- 无症状的个体往往存在未被诊断的肝脏疾病.
- 早期发现肝硬化和纤维化对于预防疾病进展至关重要.
- 广泛查肝脏健康需要使用非侵入性方法.
研究的目的:
- 查无症状,看似健康的受试者是否有显著的肝纤维化和脂肪.
- 为了评估振动控制的短暂弹性学和控制的衰减参数 (CAP) 对于这种查目的的实用性.
主要方法:
- 前性研究包括433名无症状,健康的成年人.
- 所有参与者都接受了纤维扫描/CAP检查.
- 肝硬度测量>6kPa或CAP>248dB/m的受试者进一步评估慢性肝病.
主要成果:
- 72%的受试者表现出显著的脂肪和/或纤维化.
- 确定了特定的子组:正常 (n=119),仅脂肪酸 (n=133),脂肪酸和纤维化 (n=95),仅纤维化 (n=86).
- 患有肥胖症和纤维化症的受试者都有升高的透氨酶,甘油三和总胆固醇.
结论:
- 在看似健康的受试者中发现了显著脂肪和纤维化的高患病率.
- 肝硬度测量和CAP是查无声肝病的有希望的非侵入性工具.
- 这些方法可以作为有效的第一线程序,以人口为基础的肝脏健康评估.
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