在克罗恩病中,组织治疗是否比内镜治疗更有临床价值?
Ting Zhang1, Qi-De Zhang1, Tian Jin1
1Department of Gastroenterology endoscopy center, Affiliated Hospital of Nanjing University of Chinese Medicine.
European journal of gastroenterology & hepatology
|August 14, 2023
概括
小肠内镜治疗对于缓解期的克罗恩病 (CD) 患者至关重要. 实现内镜治疗,而不是仅仅组织学治疗,似乎在临床上更有价值,用于预测复发风险.
科学领域:
- 胃肠病学 胃肠病学
- 炎症性肠道疾病研究研究
- 内镜医学是一种内镜医学.
背景情况:
- 在克罗恩病 (CD) 中小肠 (SB) 内镜治疗尚未得到充分研究.
- 评估超出临床标志物的愈合对于管理CD患者至关重要.
研究的目的:
- 评估SB内镜粘膜和CD患者组织愈合的临床意义.
- 为了确定内镜治疗是否比组织学治疗更有效地预测疾病复发.
主要方法:
- 在临床血清学缓解的99名CD患者的回顾性分析.
- 进行了结肠镜和双气球肠镜检查.
- 主要终点包括临床和血清学复发的时间.
主要成果:
- 只有43.4%的患者实现了SB内镜治疗.
- 与没有SB内镜治疗的患者相比,SB内镜治疗的患者复发率和住院率较低,尽管在统计学上并不显著.
- 在具有和没有组织学愈合的患者和内镜愈合的患者之间,没有观察到复发或住院率的显著差异.
结论:
- 在缓解期的CD患者中,很大一部分缺乏SB内镜治疗.
- SB内镜病变与临床复发的风险增加有关.
- 内镜治疗可能比组织治疗更有临床实用性,用于评估CD的缓解.
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