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在狗中 (2003-2014) 过敏反应和过敏反应的回顾性评估:86例
Fabrice T J Fosset1,2, Benjamin E G Lucas2,3, Cassandra L Wolsic2,4
1NorthStar VETS, Robbinsville Twp, New Jersey, New Jersey, USA.
概括
狗的过敏反应,通常是由疫苗引发的,有良好的预后,皮肤症状并不总是存在. 葡萄糖皮质类药物没有改善过敏反应或轻度过敏反应的狗的康复或生存率.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 免疫学 免疫学 免疫学
- 毒理学 毒理学 毒理学
背景情况:
- 过敏反应是一种严重的I型过敏反应,潜在的危及生命的后果.
- 了解犬类过敏反应的临床特征和结果对于有效管理至关重要.
- 以前的研究表明,葡萄糖皮质类药物在控制过敏反应方面起着作用,但它们在犬类过敏反应中的有效性需要进一步研究.
研究的目的:
- 描述狗的过敏反应,包括临床症状,严重程度,治疗方法,预后和估计的发病率.
- 确定葡萄糖皮质类药物对患有过敏反应和轻度过敏反应的狗的临床康复和生存的影响.
主要方法:
- 一项回顾性研究是在2003年1月1日至2014年4月28日在一所大学教学医院进行的.
- 分析了治疗I型过敏反应的86只狗,其中19只被诊断为过敏反应,67只被诊断为轻度皮肤反应.
- 收集和分析了临床症状,治疗方法 (H1抗体和葡萄皮质类药物) 和结果的数据.
主要成果:
- 据估计,过敏反应的发生率为0.04%,轻度过敏反应的发生率为0.15%.
- 疫苗是过敏反应 (57.9%) 和轻度过敏反应 (28.4%) 的最常见触发因素.
- 虽然大多数狗存活下来,但不存活与呼吸困扰和色症有关. 葡萄糖皮质醇使用与改善的临床改善或存活率没有关联.
结论:
- 狗的过敏反应通常有良好的预后,并且皮肤征兆的存在不是一个一致的特征.
- 该研究发现,使用葡萄糖皮质激素和在患有轻度I型过敏反应或过敏反应的狗中改善临床结果或生存之间没有关联.
- 进一步的研究可能是有必要的,以探索替代或辅助治疗犬类过敏反应.
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