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皮肤透脏瘤冷解效应对脏功能的影响
Jens Steensen Knudsen1,2, Louise Aarup Duus2,3, Theresa Junker2
1Department of Medicine, Faculty of Health Sciences, University of Southern Denmark (SDU), Odense, Denmark.
Journal of endourology
|August 14, 2023
概括
对于脏瘤的皮肤化 (PCA) 显示对功能的影响很小,手术后12个月. 这项研究证实PCA是一种安全有效的干预措施,即使是患者有先前存在的功能下降.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
背景情况:
- 透皮冷 (PCA) 是对脏瘤的一种成熟治疗方法.
- 对于PCA后的长期功能存在有限的数据.
- 评估功能对于评估治疗的安全性和有效性至关重要.
研究的目的:
- 评估计算机断层扫描指导PCA对功能的影响.
- 在PCA后12个月,评估估计的膜过率 (eGFR) 的变化.
主要方法:
- 对259名接受PCA治疗的脏瘤患者进行了回顾性队列研究.
- 收集了基线和12个月后的EGFR数据.
- 分析了与慢性病 (CKD) 阶段相关的eGFR变化.
主要成果:
- 平均eGFR在12个月内从73.7mL/min/1.73m2 (p < 0.0001) 降低到69.7mL/min/1.73m2 (p < 0.0001) 的最小值.
- 大多数患者在CKD阶段保持或发生最小的变化.
- 在治疗功能较好的脏中治疗的扭曲学患者中没有观察到显著的eGFR下降.
结论:
- 在治疗后一年,PCA对功能产生最小的不良影响.
- 该程序被认为是安全和相关的管理脏瘤,包括患者功能受损.
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