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Updated: Jul 19, 2025

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胚胎干细胞因子FOXD3 (创世纪) 缺陷在胃肠道 stromal 瘤中

Fabio R Faucz1, Anelia D Horvath2, Guillaume Assié3,4

  • 1Section on Endocrinology & Genetics, Program on Developmental Endocrinology & Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America.

Endocrine-related cancer
|August 14, 2023
PubMed
概括

对于发育至关重要的基因FOXD3,与胃肠道 stromal 瘤 (GISTs) 有关. 它的失活导致Cajal (ICC) 和KIT间歇细胞的过度表达增加,导致GIST的形成.

关键词:
卡尼三合一 卡尼三合一卡尼斯特拉塔基斯综合征这就是FOXD3D3的意思.这就是GIST GIST.这是Cajal的间歇细胞.

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