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Updated: Jul 19, 2025

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists

Published on: November 15, 2013

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药物发现向核受体结合SET域蛋白2 (NSD2)

Zonghui Ma1, Andrew A Bolinger1, Haiying Chen1

  • 1Chemical Biology Program, Department of Pharmacology and Toxicology, University of Texas Medical Branch (UTMB), Galveston, Texas 77555, United States.

Journal of medicinal chemistry
|August 14, 2023
PubMed
概括

核受体结合SET域蛋白 (NSDs),特别是NSD2,是癌症等疾病的关键. 针对NSD2的抑制剂,如目前正在临床试验中的KTX-1001,提供了潜在的新疗法.

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