功能监测和心房动患者的轨迹
Nathaniel M Hawkins1, Natasha Wiebe2, Jason G Andrade3
1Centre for Cardiovascular Innovation, University of British Columbia, 2775 Laurel Street, 9th Floor, Room 9123, Vancouver, BC, V5Z 1M9, Canada. nat.hawkins@ubc.ca.
Clinical and experimental nephrology
|August 14, 2023
概括
对心房动 (AF) 患者的功能监测随着病阶段的恶化而增加,大多数情况下遵循指南. 一小组有中度至重度损伤,但保持稳定.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 心房动 (AF) 和慢性病 (CKD) 经常同时存在.
- 在AF患者的脏监测频率和功能范围方面存在不确定性.
研究的目的:
- 评估心房动患者的功能监测频率和范围.
- 为了评估脏疾病改善全球结果 (KDIGO) 关于对AF患者脏监测的指南的遵守.
主要方法:
- 使用ICD代码识别了患有AF的阿尔伯塔成年人 (2008-2017年).
- 通过使用eGFR和白尿定义了KDIGO风险类别.
- 从基线到一年内最大的eGFR轨迹进行比较.
主要成果:
- 16.0%的eGFR≥90,49.0%的G2 (60-89.9),19.8%的G3a (45-59.9),11.4%的G3b (30-44.9),3.8%的G4 (15-29.9) 均为90以上的EGFR.
- 脏监测频率在较低的eGFR和更严重的白色素尿时增加,每年约2至8倍.
- 60-80%的患者接受了指南推的监测;EGFR下降随着基线功能下降而增加.
结论:
- 在AF患者中,脏监测频率与KDIGO风险类别恶化相关.
- 大约75%的患者接受了指导方针建议的监测.
- 大多数中度至重度EGFR损伤的患者在一年内保持稳定.
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