围产期注射性阿片类抗体疗法 (IOAT) 管理:一个案例系列
Charissa J Patricelli1, Jessie Chai, Shanlea Gordon
1From the Families in Recovery (FIR) Unit, BC Women's Hospital and Health Centre, Vancouver, BC, Canada (CJP, SG, IJG, NC, KS, VP); Women's Health Research Institute, Vancouver, BC, Canada (CJP, JC, SG, IJG, KU, AA); Department of Family Practice, University of British Columbia, Vancouver, BC, Canada (CJP); University of British Columbia Faculty of Medicine, Vancouver BC, Canada (JC); Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, BC, Canada (AA); Department of Public Health and Social Policy, University of Victoria, Victoria, BC, Canada (KU).
注射性阿片类激素治疗 (iOAT) 可以稳定孕妇和产后患者的阿片类药物使用障碍. 这一案例系列表明iOAT可以在围产期治疗期间支持孕产妇和婴儿健康结果.
科学领域:
- 产周医学 产周医学
- 成精神病学成精神病学
- 孕产妇与胎儿的医学
背景情况:
- 在怀孕期间未经治疗的阿片类药物使用障碍 (OUD) 对母亲和胎儿构成风险.
- 注射性阿片类激素治疗 (iOAT) 是对严重的OUD的密集治疗,但围产期数据很少.
研究的目的:
- 介绍关于围产期IOAT的第一个案例系列.
- 评估iOAT在孕妇和产后患者的可行性和结果.
主要方法:
- 追溯图表审查和前性调查13名参与者接受IOAT (静脉注射海德罗摩) 在加拿大围产稳定单位.
- 收集关于社会人口统计,治疗和母亲/婴儿结果的数据.
主要成果:
- 参与者在怀孕期间 (n=5) 或分娩后 (n=8) 平均接受IOAT23天.
- 大多数参与者成功地与婴儿一起过渡到门诊护理,婴儿在健康状态下出院.
- 婴儿接受了新生儿口服吗啡,并健康地出院.
结论:
- 这个案例系列是第一个在周边时期描述IOAT的案例系列.
- iOAT可以稳定围产期个体的OUD,改善参与和留在护理中的时间.
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