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Updated: Jul 19, 2025

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
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Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

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生殖基因EGFR突变和家族肺癌

Geoffrey R Oxnard1, Ruthia Chen1, Jennifer C Pharr1

  • 1Dana-Farber Cancer Institute, Boston, MA.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
|August 14, 2023
PubMed
概括

遗传性肺癌风险与生殖线EGFR致病变体 (PVs) 相关,特别是EGFR T790M,主要在美国东南部发现. 这种创始变种显示出可变的透性,受影响的载体经常发展为肺腺癌和结节.

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