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Updated: Jul 19, 2025

Purification and Aggregation of the Amyloid Precursor Protein Intracellular Domain
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Purification and Aggregation of the Amyloid Precursor Protein Intracellular Domain

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由APPI衍生的循环增强Aβ42聚合并减少Aβ42介导的膜不稳定性和细胞毒性

Shiran Lacham-Hartman1, Reut Moshe1, Shani Ben-Zichri2

  • 1Avram and Stella Goldstein-Goren Department of Biotechnology Engineering and the National Institute of Biotechnology in the Negev, Ben-Gurion University of the Negev, P.O. Box 653, Beer-Sheva 84105, Israel.

ACS chemical neuroscience
|August 14, 2023
PubMed
概括

一种针对粉样β 42 (Aβ42) 的新型循环增强了聚合物形成,降低了阿尔茨海默病 (AD) 模型中的神经毒性. 这种可以通过调节Aβ42聚合来开发新的AD疗法.

关键词:
这是一个很好的应用程序.阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.Aβ42 Aβ42 Aβ42 Aβ42 Aβ42 Aβ42 Aβ42 Aβ42 Aβ42人造膜 人造膜神经元细胞毒性的毒性类脂类相互作用.

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