来自药用下层植物的多糖的抗瘤作用:一篇综述
1State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
International journal of biological macromolecules
|August 14, 2023
概括
药用下层植物多糖体 (MLPPs) 对各种癌症具有显著的抗瘤活性. 这些天然化合物为传统的癌症治疗提供了有希望的替代方案,副作用较少.
科学领域:
- 药理学 药理学是指药理学的学科.
- 自然产品 自然产品
- 在瘤学瘤学.
背景情况:
- 癌症仍然是全球主要的死亡原因,目前的治疗方法会导致严重的副作用.
- 迫切需要新型抗癌药物,具有更好的安全性.
- 来自较低植物的多糖,称为药用较低植物多糖 (MLPPs),表现出强大的抗瘤特性.
研究的目的:
- 审查具有抗瘤活性的MLPPs的结构和作用机制.
- 讨论MLPPs在癌症治疗中的当前应用.
- 探索MLPP在瘤学的未来潜力和发展.
主要方法:
- 关于下层植物药用多糖的研究文献综述.
- 分析MLPPs的化学结构.
- 检查了MLPPs抗瘤作用背后的拟议机制.
- 关于MLPPs在癌症治疗中的临床前和临床应用的审查.
主要成果:
- MLPPs具有多样化的化学结构,并在各种癌症类型中表现出显著的抗瘤活性.
- 作用机制包括免疫调节,直接的细胞毒性作用和瘤生长抑制.
- 在食品和制药应用中,MLPPs在癌症管理方面都显示出潜力.
结论:
- 药用较低植物多糖体代表了癌症治疗的自然化合物的有前途的类别.
- 进一步研究它们的结构-活性关系和临床疗效是有必要的.
- MLPP具有显著的发展潜力,可以作为安全有效的抗癌剂.
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