单生子活产后与重大胎儿形相关的母亲不良后果
Tetsuya Kawakita1, Gustavo Vilchez2, Lea Nehme1
1Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, VA (Drs Kawakita and Nehme).
American journal of obstetrics & gynecology MFM
|August 14, 2023
概括
重大和轻微的胎儿形显著增加严重的孕产妇发病率和其他妊娠并发症的风险. 这些先天性疾病是对母亲不良后果的独立风险因素.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 公共卫生 公共卫生
背景情况:
- 主要的胎儿形发生在2%至5%的活产儿中.
- 胎儿形对严重的孕产妇发病率的影响尚不清楚.
- 这项研究调查了胎儿形和母亲健康并发症之间的关联.
研究的目的:
- 为了比较母亲在怀孕期间的结果,与那些没有重大或轻微的胎儿形相比.
- 为了确定与胎儿形相关的特定的孕产妇并发症.
- 在胎儿异常存在的情况下,量化严重孕产妇发病率的风险.
主要方法:
- 安全劳动协会数据库的二次分析.
- 包括有单个活产的孕妇.
- 根据疾病预防控制中心的标准,将胎儿形分为重大或轻微的分类.
- 使用CDC标准定义严重的孕产妇发病率.
- 使用波桑回归来计算调整后的相对风险的统计分析.
主要成果:
- 主要胎儿形与51%的严重孕产妇发病率风险增加有关.
- 轻微的胎儿形与73%更高的严重孕产妇发病风险和4.5倍增加的孕产妇死亡风险有关.
- 无论是重大还是轻微的胎儿形都增加了产后出血,孕前和剖腹产的风险.
结论:
- 重大和轻微的先天性胎儿形是严重的孕产妇发病率的独立风险因素.
- 胎儿形与一系列其他重大妊娠并发症有关.
- 这些发现强调了在对母亲的风险评估中考虑胎儿异常的重要性.
相关概念视频
Teratogenicity
2.5K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.5K
Meiosis vs. Mitosis
57.1K
Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
57.1K
Pathophysiology of Diabetes
989
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
989
Fetal Circulation
1.1K
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
1.1K
Neurulation
42.1K
Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
42.1K
Mitral Valve Prolapse III: Nursing Management
16
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
16


