世界贸易中心的喘和创伤后应激障碍的工人更准确地感知到空气流量限制
Juan P Wisnivesky1, Nikita Agrawal2, Jyoti Ankam3
1Division of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Pulmonary and Critical Care Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
概括
创伤后应激障碍 (PTSD) 与世界贸易中心 (WTC) 工人喘控制的恶化有关. 这可能是由于对空气流量限制的感知变化,而不是肺功能差异.
科学领域:
- 环境健康 环境健康
- 精神病学是一个精神病学.
- 肺部病理学 肺部病理学
背景情况:
- 创伤后应激障碍 (PTSD) 是世界贸易中心 (WTC) 工作人员喘发病率增加的重要危险因素.
- 了解将PTSD和喘恶化联系在一起的机制对于这个人群至关重要.
研究的目的:
- 调查改变对空气流量限制的感知是否调解了PTSD和WTC工人中较差的喘控制之间的关联.
- 为了比较客观的肺功能测量 (PEF) 和主观的感知 WTC 工人与没有 PTSD 的空气流限制.
主要方法:
- 从224名WTC工人收集的数据包括喘控制评估 (ACQ,AQLQ) 和6周的每日峰值呼气流 (PEF).
- 对空气流量限制的感知通过比较猜测与实际的PEF值来评估.
- 使用结构化临床访谈证实了PTSD诊断;统计模型比较了PEF和感知度.
主要成果:
- 创伤后应激障碍与明显更差的喘控制得分 (ACQ和AQLQ) 相关.
- 在患有PTSD和没有PTSD的WTC工人之间,每日PEF测量没有发现显著差异.
- 患有PTSD的WTC工人表现出更高比例的准确感知和减少对空气流限制的低感知.
结论:
- 对空气流量限制的感知差异可能会调解PTSD与WTC工人的喘症状增加之间的关系.
- 尽管有相似的客观肺功能,但PTSD影响了WTC工人如何感知他们的喘,影响了自我报告的控制.
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