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Updated: Jul 19, 2025

Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats
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Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats

Published on: November 8, 2018

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珍珠和:在依赖的皮里多克辛患者中对皮里多克辛的延迟反应

Olivier Fortin1, Kelsey Christoffel2, Youssef Kousa2

  • 1From the Prenatal Pediatrics Institute (O.F., K.C., Y.K., S.B.M.), Children's National Hospital; Department of Neurology (Y.K., S.B.M., T.A.), and Department of Pediatrics (Y.K., K.D., S.B.M., T.A.), The George Washington University School of Medicine and Health Sciences; Division of Neurology (Y.K., T.A.), Division of Medical Genetics (I.M., E.L.), Rare Disease Institute (I.M., E.L.), and Division of Neonatology (K.D.), Children's National Hospital, Washington, DC. ofortin@childrensnational.org.

Neurology
|August 14, 2023
PubMed
概括

金素依赖性 (PDE) 是一种遗传性疾病,导致新生儿发作. 虽然素 (维生素B6) 可以帮助,但临床改善可能是渐进的,需要继续治疗.

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Ezocgabine or retigabine, an antiepileptic drug of remarkable efficacy, has revolutionized the management of seizures. It is a potassium channel activator, explicitly targeting the family of Q subtype potassium channels. It enhances the transmembrane potassium currents, regulating neuronal excitability. This action stabilizes the resting membrane potential, a pivotal factor in mitigating the hyperexcitability that characterizes epilepsy.
Ezogabine has gained approval as an adjunctive treatment...
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