心理和行为参与者内部预测者对口服艾滋病毒暴露前预防 (PrEP) 的坚持
Alison Taylor1, Rosalie Hayes2, Nneka Nwokolo3
1Department of Psychology, Royal Holloway University of London, London, UK.
AIDS and behavior
|August 14, 2023
概括
了解每日暴露前预防 (PrEP) 不遵守的预测因素对于预防艾滋病毒至关重要. 情境因素,如当天的非正常性和物质使用显著影响与男性发生性关系的男性的坚持.
科学领域:
- 公共卫生 公共卫生
- 行为科学 行为科学
- 预防艾滋病毒 预防艾滋病毒
背景情况:
- 口服暴露前预防 (PrEP) 是有效的预防艾滋病毒,但依赖于一致的坚持.
- 不遵守PrEP是常见的,了解其预测因素对于改善结果至关重要.
研究的目的:
- 为了确定PrEP不遵守的参与者内部预测因素.
- 探索与错过PrEP剂量相关的情境和个人因素.
主要方法:
- 横截面,参与者内部的研究设计.
- 67名同性恋,双性恋和其他与男性发生性关系的男性 (MSM) 每天接受PrEP.
- 基于信息动机行为技能模型的问卷,比较了附属和非附属的情节.
主要成果:
- 与 PrEP 不遵守有关的一天的非正常性,不在家,周末的日子,有公司,和物质使用.
- 较低的PrEP信息,行为技能和较少的积极影响也预测了不坚持.
- 不使用提醒与遗漏剂量有关.
结论:
- 情境变化是PrEP不遵守的关键预测因素.
- 坚持干预措施应应对上下文因素,并支持技能建设.
- 专注于情境依附策略可以提高PrEP的有效性.
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