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Updated: Jun 18, 2026

Single-cell Gene Expression Using Multiplex RT-qPCR to Characterize Heterogeneity of Rare Lymphoid Populations
10:23

Single-cell Gene Expression Using Multiplex RT-qPCR to Characterize Heterogeneity of Rare Lymphoid Populations

Published on: January 19, 2017

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对人类MAIT细胞转录,功能和克隆多样性的单细胞分析

Lucy C Garner1, Ali Amini2, Michael E B FitzPatrick2

  • 1Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK. lucy.garner@ndm.ox.ac.uk.

Nature immunology
|August 14, 2023
PubMed
概括

人类粘膜关联不变T细胞 (MAIT) 具有多种功能和克隆类型,因组织和刺激而有所不同. 它们的克隆身份会影响基因表达,但不会影响IL-17的产生.

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A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations

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Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq06:24

Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility Using scRNA-Seq and scATAC-Seq

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相关概念视频

T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...