横性肝活检:扩大肝活检的适用性,提供可靠的诊断质量
Miao-Yang Chen1, An-Yin Yang1, Yi-Fan Hu1
1Department of liver diseases, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, No.1 Zhongfu Road, Gulou District, Nanjing, 210003, China.
BMC gastroenterology
|August 14, 2023
概括
经肝活检 (TJLB) 和皮肤肝活检 (PLB) 的安全性和诊断效率相似. TJLB为肝活检提供了可靠的替代方案,扩大了其临床适用范围.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 干预性放射学 干预性放射学
- 诊断程序 诊断程序 诊断程序
背景情况:
- 肝活检并发症和诊断效率是临床关键问题.
- 评估不同肝脏活检技术的安全性和有效性对于患者护理至关重要.
研究的目的:
- 为了比较穿肝活检 (TJLB) 与皮肤肝活检 (PLB) 的安全性和有效性.
- 通过倾向性得分匹配 (PSM) 来评估TJLB和PLB之间的诊断质量和并发症率.
主要方法:
- 对TJLB和PLB患者的临床和病理数据的回顾性分析 (2012年1月 - 2022年10月).
- 倾向性得分匹配 (PSM) 用于平衡患者特征,不包括凝血指数.
- 关键的匹配因素包括肝功能,肝病状况和患者人口统计.
主要成果:
- 在PSM之后,分析了75名患者 (25名TJLB,50名PLB). 并发症发生率相似 (TJLB为4.0%,PLB为10.0%,P>0.05).
- 在TJLB中,平均样本长度显著缩短 (10.0mm与16.5mm相比,P<0.05),完整的门道更少 (6.0与10.0,P<0.05).
- 不知病因的肝病变的诊断效率在两组之间是可比的 (95.7%的TJLB对比93.2%的PLB后匹配,P>0.05).
结论:
- 横肝活检 (TJLB) 是一种安全有效的侵入性诊断程序.
- TJLB提供了可靠的诊断质量,并扩大了肝活检的指示.
- 无论是TJLB还是PLB,都在评估肝脏疾病方面表现出高的诊断效率.
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