心理测量EQ-5D-5L的属性,用于用在患有格雷夫斯病的患者身上
Xiaodong Liu1, Wendy Wl Chan2, Eric Hm Tang3
1Department of Surgery, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China.
Health and quality of life outcomes
|August 14, 2023
概括
EQ-5D-5L有效地测量了Graves病患者的健康状况,显示出良好的有效性和可靠性. 它准确地反映了随着时间的推移健康状况的变化.
科学领域:
- 内分泌学 在内分泌学.
- 健康 结果 研究 研究 结果
- 心理测量 心理测量 心理测量
背景情况:
- EQ-5D-5L是广泛使用的通用健康状况测量仪.
- 格雷夫斯病 (GD) 是一种常见的内分泌疾病,影响甲状腺功能.
研究的目的:
- 评估EQ-5D-5L在患有格雷夫斯病的患者中的心理测量特性.
- 在这个群体中评估EQ-5D-5L的融合有效性,测试-重新测试可靠性和响应性.
主要方法:
- 在香港对125名GD患者进行前性队列研究.
- EQ-5D-5L和ThyPRO-39问卷在基线,1个月和6个月的随访时间进行.
- 用斯皮尔曼相关性,类内相关系数 (ICC),Gwet的AC2和效果大小统计 (SES,SRM) 评估的心理测量属性.
主要成果:
- 在EQ-5D-5L和ThyPRO-39分数之间观察到中度至强度的相关性,支持融合有效性.
- 在Gwet的AC2和大多数EQ-5D-5L领域 (例如,自我照顾,移动性) 的高协议率.
- EQ-5D-5L表现出对健康状况恶化的反应,EQ-VAS和EQ-5D-5L指数的效果大小显著.
结论:
- EQ-5D-5L是评估格雷夫斯病患者健康状况的有效和可靠措施.
- 该仪器对健康状况的变化反应良好,因此适合进行纵向研究.
- 这些发现支持在临床实践和研究中使用EQ-5D-5L来治疗格雷夫斯病.
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