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对于妊娠年龄的早产婴儿来说小,以后的脂肪和身高:系统性审查和元分析
Seham Elmrayed1,2,3,4,5, Jahaira Pinto6, Suzanne C Tough1,2,3
1Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Paediatric and perinatal epidemiology
|August 15, 2023
概括
妊娠年龄 (SGA) 过早出生的婴儿在以后的生活中具有较低的体重,腰围,瘦质量和身高. 在早产SGA和非SGA婴儿之间,肥胖度没有差异.
科学领域:
- 儿科健康 儿科健康
- 新生儿科学 新生儿科学
- 增长和发展 增长和发展
背景情况:
- 超重和肥胖是全球重要的健康问题.
- 过多脂肪的潜在来源可能从胎儿生命中开始.
- 目前尚不清楚这是否适用于早产婴儿.
研究的目的:
- 评估SGA出生和早产婴儿晚期肥胖和身高之间的关联.
- 根据妊娠年龄分类,研究早产婴儿的长期生长结果.
- 检查早产SGA和非SGA种群之间的人类学差异.
主要方法:
- 系统审查和对2022年10月之前发表的研究进行元分析.
- 包括的研究报告了SGA与非SGA分类的早产婴儿的人类测量结果 (脂肪和身高).
- 数据提取和偏差风险评估是重复执行的.
主要成果:
- 对39项研究 (n>30,000) 的元分析显示,与非SGA早产婴儿相比,早产SGA婴儿的BMI,腰围,肌肉质量和身高都较低.
- 具体发现包括-0.66kg/m2更低的BMI和-3.85cm更低的身高.
- 在各种脂肪度量测量中没有发现显著差异,尽管对一些人的统计能力是有限的.
结论:
- 与非SGA早产的同龄人相比,早产婴儿在晚年生活中表现出较低的BMI,腰围,瘦体质和身高.
- 在SGA早产组和非SGA早产组之间没有观察到显著的脂肪差异.
- 这些发现强调了基于SGA状态的早产婴儿的独特长期生长轨迹.
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