使用囊泡成像-报告和数据系统和明显扩散系数区分膀癌的阶段
Wei Liu1,2, Ruchuan Chen1,3, Xiaohang Liu1,2
1Department of Radiology, Fudan University Shanghai Cancer Center, Shanghai, China.
Quantitative imaging in medicine and surgery
|August 15, 2023
概括
多参数MRI,使用膀成像报告和数据系统 (VI-RADS) 和明显扩散系数 (ADC) 组图分析,准确地区分早期膀癌 (BC) 和晚期癌症. 将VI-RADS与ADC直方图参数结合起来,可以提高BC分期的诊断性能.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 精确的手术前T分期对于膀癌 (BC) 治疗和预后至关重要.
- 目前的BC手术前T分期方法存在挑战.
- 多参数磁共振成像 (mpMRI) 显示了提高BC分期精度的潜力.
研究的目的:
- 为了评估膀成像报告和数据系统 (VI-RADS) 和体积明显扩散系数 (ADC) 基因组参数的诊断性能.
- 使用mpMRI,区分T2阶段及以下 (≤T2) 与T3阶段及以上 (≥T3) 的BCs.
- 在BC分期中评估VI-RADS和ADC直方图参数的综合值.
主要方法:
- 包括62名病理确诊的BC.患者.
- 放射科医生使用VI-RADS系统对瘤进行了评分.
- 从ADC地图中提取了体积计ADC历史图参数.
- 统计分析包括Cochran-Armitage和曼-惠特尼U测试.
- 使用接收机操作特征 (ROC) 曲线分析来评估预测功率.
主要成果:
- 与≥T3阶段BC相比,≤T2阶段BC的ADC组图参数 (最小,平均,中位,最大,百分位) 显着更高.
- 倾斜性和曲性呈现出相反的趋势.
- VI-RADS实现了曲线下的面积 (AUC) 为0.834.
- 结合VI-RADS与曲性和曲性,AUC (0.915) 显著高于单独使用VI-RADS.
结论:
- 在VI-RADS和体积ADC组图分析中,有效地区分了≤T2和≥T3阶段的BC.
- 卷度ADC直方图分析提供了补充信息,以提高VI-RADS的性能.
- 这些mpMRI技术为手术前的BC分期提供了宝贵的工具.
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