与猫长期双酸盐治疗相关的不足骨折的管理
Lauren M Meneghetti1, Karen L Perry1
1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA.
JFMS open reports
|August 15, 2023
概括
在猫中长期使用双酸盐可能会增加缺陷骨折的风险,类似于人类. 虽然骨折修复是可能的,但在接受双酸盐治疗的猫中,应预期延迟愈合.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 整形外科手术 整形外科手术
- 药理学 药理学是指药理学的学科.
背景情况:
- 异常性高血症是猫的一种常见疾病.
- 双酸盐,如阿伦德罗酸盐,用于管理高血症.
- 长期使用双酸盐与人类的缺陷骨折有关.
研究的目的:
- 报告一例猫在长期双酸盐治疗期间经历了无创性不足骨折的病例.
- 调查双酸盐治疗与猫的缺陷骨折之间的潜在关联.
- 提供对接受双酸盐的猫的骨折管理和愈合的见解.
主要方法:
- 一只10岁的猫患有异常性高血症,在慢性阿伦德罗纳特治疗中出现了骨和骨骨折.
- 骨骨折的治疗方式是非手术.
- 骨折经历了开放式缩小和内部固定.
- 停止服用阿伦德罗纳特,并用普雷尼索隆替代,以治疗高血症.
主要成果:
- 这只猫经历了骨和骨的无创性缺陷骨折.
- 骨骨折显示愈合延迟,在术后22周实现结合.
- 猫在17个月后恢复良好,没有植入物并发症或进一步的骨折.
- 超血症仍然可以用普雷迪尼索隆控制.
结论:
- 这一案例表明,长期使用双酸盐与猫的不足骨折之间可能存在关联.
- 在长期接受双酸盐治疗的猫群中,可能需要进行连续的放射性监测.
- 以前接触过双酸盐的猫的骨折修复可能是成功的,但需要预期延迟愈合.
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