在日本,亚形性皮肤炎的儿科患者的疾病负担
Yukihiro Ohya1, Hidehisa Saeki2, Hisakatsu Nawata3
1Allergy Center, National Center for Child Health and Development, Tokyo, Japan.
Pediatric dermatology
|August 15, 2023
概括
这项研究发现,日本儿童中阿托皮性皮肤炎 (AD) 严重程度的增加显著加剧了症状,爆发,并发症,并影响了生活质量. 更大的AD严重程度导致儿童患者的疾病负担更高.
科学领域:
- 皮肤病学 皮肤病学
- 儿科 儿科 儿科
- 流行病学 流行病学
背景情况:
- 亚托皮炎 (AD) 是一种慢性皮肤疾病,影响儿科患者的生活质量.
- 在真实世界的儿童的流行病学与亚托皮肤炎报告他们的经验 (ECO-DE) 研究调查了在日本的AD负担.
研究的目的:
- 评估亚托皮性皮肤炎严重程度对日本儿科患者疾病负担的影响.
- 评估AD严重程度和症状,爆发,并发症,医疗保健使用和生活质量之间的关系.
主要方法:
- 一项在线调查对日本儿童和青少年 (6个月至17岁) 和他们的照顾者进行了调查.
- 使用面向患者的湿疹测量 (POEM) 评估了疾病的严重程度.
- 收集的数据包括阿尔茨海默病的症状,爆发,并发症,医疗保健资源利用率,缺学率和与健康有关的生活质量 (HRQoL).
主要成果:
- 在被诊断为AD的547名儿科患者中,63.3%的患者患有明显/轻度,32.5%的中度和4.4%的严重疾病,基于POEM分数.
- 增加的AD严重程度与更严重的症状 (,疼痛,睡眠障碍),增加的爆发和较高的亚托皮性并发症率相关.
- 更大的AD严重程度也与医疗保健利用率的增加,更多的错过学校日和所有年龄组的HRQoL降低有关.
结论:
- 这项以人口为基础的研究表明,阿托皮性皮肤炎严重程度对日本儿童和青少年的疾病负担有重大影响.
- 较高的AD严重程度与对患者福祉和日常生活的重大负面影响有关.
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