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改善与双相情感障碍相关的兴奋的药物治疗方法
Justin Faden1, Joseph F Goldberg2, Leslie Citrome3
1Department of Psychiatry and Behavioral Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Expert opinion on pharmacotherapy
|August 15, 2023
概括
由于选择有限,在双相情感障碍中管理激动是具有挑战性的. 较新的吸入和舌下治疗方法为急性躁狂发作提供了快速缓解.
科学领域:
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
- 临床医学 临床医学
背景情况:
- 兴奋是双相情感障碍中常见且具有挑战性的症状,特别是在躁狂发作期间.
- 目前已批准了有限的药理选择,用于管理这种患者群体的急性激动症.
研究的目的:
- 审查当前的药理疗法对双相情感障碍的急性兴奋的景观.
- 为了比较可用的治疗方案的疗效,耐受性和可用性.
主要方法:
- 使用PubMed.gov.gov进行了全面的文献搜索.
- 包括英语临床试验,评论和元分析.
- 搜索术语包括"双极性障碍"和"激动".
主要成果:
- 经批准的药理学药物表现出类似的疗效,但在耐受性和易于使用方面有所不同.
- 基于患者个人资料的个性化治疗选择至关重要.
- 新的选择,如吸入的洛克萨和舌下德克斯梅德托米丁,提供了快速的开始,可能适合合作的患者.
结论:
- 临床医生可以根据药物概况来个性化治疗双相情感障碍中的急性激动症.
- 建议对轻度至中度激动进行早期干预,以防止升级.
- 新型,快速起作用的药物为管理激动提供了有价值的替代品.
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