最近的进展和酸剂结合物的应用,用于向瘤细胞
Vahab Alamdari-Palangi1, Khojaste Rahimi Jaberi2, Mahshid Shahverdi3
1Department of Molecular Medicine, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, 7133654361, Iran.
Journal of cancer research and clinical oncology
|August 15, 2023
概括
抗癌 (ACP) 提供高特异性和快速细胞杀伤的向癌症治疗. 改性,包括疫苗和药物合物,在克服局限性和推进癌症治疗方面表现有前途.
科学领域:
- 在瘤学瘤学.
- 生物化学 生物化学
- 药理学 药理学是指药理学的学科.
背景情况:
- 癌症仍然是医学和科学界面临的重大挑战.
- 类治疗药物越来越多地用于各种医疗应用,包括癌症治疗.
研究的目的:
- 审查抗癌 (ACP) 在癌症治疗中的当前状态和未来潜力.
- 专注于开发用于癌症治疗的类疫苗和类药物联合体.
主要方法:
- 审查关于抗癌的现有文献.
- 对基于的癌症疗法的当前临床试验数据的分析.
- 检查了非洲和非洲国家和地区 (ACP) 的行动机制.
主要成果:
- 超过60种天然和合成的酸已被批准用于治疗癌症和其他疾病.
- ACPs作为化学疗法和放射性核素的直接细胞毒剂或载体,专门针对癌细胞.
- ACPs通过诸如膜破坏,亡,亡,自和免疫系统调节等机制诱导癌细胞死亡.
结论:
- 抗癌代表了癌症治疗的有前途的治疗策略,特别是类疫苗和类药物合物.
- 修改过的具有克服诸如低代谢稳定性和低生物可用性等局限性的潜力.
- 抗癌细胞表现出针对癌细胞的多种机制,包括诱导细胞亡,直接细胞溶解,抗血管生成,自介导细胞死亡和免疫调节.
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