PET FDG CT对于巨细胞动脉炎与孤立的咳有用
Florent L Besson1, Arsene Mekinian2
1Nuclear Medicine Department, Kremlin Bicetre Hospital, APHP, Kremlin Bicetre, France.
巨细胞动脉炎 (GCA),一种大血管血管炎,很少会与孤立的干咳一起出现. 这种罕见的症状通常对类固醇有反应,有助于诊断.
科学领域:
- 类风湿病学 类风湿病学
- 内部医学 内部医学
- 血管医学 血管医学
背景情况:
- 巨细胞动脉炎 (GCA) 是一种常见的血管炎,影响大和中等动脉,通常在50岁以上的人群中.
- 经典症状包括头痛,关节障碍和多肌痛类风湿症,但也可能出现不典型的表现.
研究的目的:
- 为了调查巨细胞关节炎中孤立干咳的罕见表现.
- 审查现有的文献和关于GCA与咳的病例系列.
- 评估这种特定的GCA表现的诊断和治疗方法.
主要方法:
- 对病例报告和病例系列的综合文献综述,重点是咳的GCA.
- 分析患者的人口统计,临床表现,成像发现和治疗反应.
- 包括13个案例报告与现有数据和一个案例系列.
主要成果:
- 大多数受影响的患者是男性,呈现出孤立的咳或与发烧和体重减轻相关的咳.
- 虽然大动脉壁Angio-CT扫描通常是正常的,但FDG PET-CT始终显示出异常的胸腔动脉吸收.
- 动脉活检通常表明GCA,咳症状对皮质类固醇治疗的反应很快.
结论:
- 孤立的干咳是极其罕见的 (<5%),但巨细胞动脉炎的明显表现.
- 在这些情况下,FDG PET-CT是一种有价值的成像方式,用于检测胸腔动脉炎症.
- 与GCA相关的咳对类固醇治疗表现出良好的反应,通常不需要额外的疗法.
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